ea0073pep4.2 | Presented ePosters 4: Reproductive and Developmental Endocrinology | ECE2021
Bruno Carmine
, Vergani Edoardo
, Napodano Cecilia
, Pocino Krizia
, Stefanile Annunziata
, Gulli Francesca
, Oliva Alessandro
, Basile Umberto
, Mancini Antonio
ObjectivePolicystic ovary syndrome (PCOS) is a multifactorial disease characterized by reproductive and metabolic impairments. PCOS patients could present anovulation, hirsutism and infertility as well as higher prevalence of metabolic syndrome, glucose intolerance and diabetes. Insulin-resistance (IR) together with hyperandrogenism represent the main players, with reciprocal influences in a vicious circle: insulin promotes androgen secretion in thecal c...